Assessment of Safety and Efficacy of Combined Trabectedin and Low-Dose Radiotherapy for Patients With Metastatic Soft-Tissue Sarcomas: A Nonrandomized Phase 1/2 Clinical Trial.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2019.6584
Abstract: Importance Active therapeutic combinations, such as trabectedin and radiotherapy, offer potentially higher dimensional response in second-line treatment of advanced soft-tissue sarcomas. Dimensional response can be relevant both for symptom relief and for survival. Objective To… read more here.
Keywords: phase; metastatic soft; soft tissue; radiotherapy ... See more keywords
Metastatic adult-type non-rhabdomyosarcoma soft tissue sarcomas in children and adolescents: A cohort study from the European paediatric Soft tissue sarcoma Study Group.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer"
DOI: 10.1002/cncr.34814
Abstract: BACKGROUND Limited data exist on the clinical behavior of pediatric non-rhabdomyosarcoma soft tissue sarcomas (NRSTS) with distant metastases at onset, and a clear standard of care has not yet been defined. METHODS This cohort study… read more here.
Keywords: tissue sarcomas; soft tissue; non rhabdomyosarcoma; tissue ... See more keywords
Brazilian consensus on the diagnosis and treatment of extremities soft tissue sarcomas
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.25847
Abstract: Soft tissue sarcomas (STSs) are rare tumors and constitute only 1% of all tumors in adults. Indeed, due to their rarity, most cases in Brazil are not treated according to primary international guidelines. read more here.
Keywords: consensus diagnosis; tissue sarcomas; soft tissue; brazilian consensus ... See more keywords
Fungation in soft tissue sarcomas is associated with poor survival
Sign Up to like & getrecommendations! Published in 2017 at "International Orthopaedics"
DOI: 10.1007/s00264-017-3628-6
Abstract: PurposeWhilst much is known on the multiple variables associated with a poor prognosis in soft tissue sarcomas, little evidence exists on the impact of fungation at the time of presentation. The aim of this study… read more here.
Keywords: poor prognosis; soft tissue; associated poor; tissue sarcomas ... See more keywords
Proteomic and Metabolomic Profiling in Soft Tissue Sarcomas
Sign Up to like & getrecommendations! Published in 2022 at "Current Treatment Options in Oncology"
DOI: 10.1007/s11864-022-00947-3
Abstract: Advances in proteomic and metabolomic technologies have accelerated our understanding of multiple aspects of cancer biology across distinct tumour types. Here we review the current state-of-the-art in the use of proteomics and metabolomics in soft… read more here.
Keywords: tissue sarcomas; proteomic metabolomic; metabolomic profiling; soft tissue ... See more keywords
Prognostic value of neutrophil-to-lymphocyte ratio and other inflammatory markers in patients with high-risk soft tissue sarcomas
Sign Up to like & getrecommendations! Published in 2020 at "Clinical and Translational Oncology"
DOI: 10.1007/s12094-020-02324-8
Abstract: Background Soft tissue sarcomas (STS) have a high risk of relapse in spite of the use of (neo)adjuvant chemotherapy. In this context, looking for new prognostic biomarkers is an interesting field of research. Our aim… read more here.
Keywords: soft tissue; high risk; ratio; tissue sarcomas ... See more keywords
Overview of malignant soft-tissue sarcomas of the limbs.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical radiology"
DOI: 10.1016/j.crad.2021.08.011
Abstract: Although soft-tissue masses are common, sarcomas are rare malignant neoplasms showing variable mesenchymal differentiation and can occur at any anatomical site. Limb soft-tissue sarcomas (STS) are rare, but often lethal tumours. Although there are scores… read more here.
Keywords: sarcoma; soft tissue; overview malignant; tissue ... See more keywords
Imaging Response Evaluation after Neoadjuvant Treatment in Soft Tissue Sarcomas: Where Do We Stand?
Sign Up to like & getrecommendations! Published in 2021 at "Critical reviews in oncology/hematology"
DOI: 10.1016/j.critrevonc.2021.103309
Abstract: Soft tissue sarcomas (STS) represent a broad family of rare tumours for which surgery with radiotherapy represents first-line treatment. Recently, neoadjuvant chemo-radiotherapy has been increasingly used in high-risk patients in an effort to reduce surgical… read more here.
Keywords: soft tissue; response; neoadjuvant treatment; treatment ... See more keywords
PDGFRα inhibition in soft-tissue sarcomas: Have we gotten it all wrong?
Sign Up to like & getrecommendations! Published in 2019 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2019.01.062
Abstract: Soft-tissue sarcomas (STS) are a wide group of rare cancers of mesendothelial cells. Its inhibition might therefore also have indirect and enchymal origin. Treatment modalities include surgery, radiotherapy and chemotherapy,mostly depending on the stage of… read more here.
Keywords: trial; soft tissue; inhibition; tissue sarcomas ... See more keywords
Abnormal vascularization of soft-tissue sarcomas on conventional MRI: Diagnostic and prognostic values.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of radiology"
DOI: 10.1016/j.ejrad.2019.06.007
Abstract: PURPOSE To assess the prevalence of abnormal vessels inside and surrounding soft-tissue sarcomas (STS) on conventional MRIs so as to evaluate their correlations with particular histotypes, histological grades, and prognosis. METHOD This single-center retrospective study… read more here.
Keywords: tumoral 157; flow voids; peri tumoral; tissue sarcomas ... See more keywords
Investigating the role of functional imaging in the management of soft-tissue sarcomas of the extremities
Sign Up to like & getrecommendations! Published in 2018 at "Physics and Imaging in Radiation Oncology"
DOI: 10.1016/j.phro.2018.05.003
Abstract: Highlights • We acquired FDG-PET, FMISO-PET, DW-MRI and DCE-MRI for 18 soft-tissue sarcomas.• We investigated the complementarity and evolution of imaging data over time.• We used textural biomarkers to identify patients who could benefit from… read more here.
Keywords: role functional; investigating role; tissue sarcomas; soft tissue ... See more keywords