Harnessing the Utility of Ex Vivo Patient Prostate Tissue Slice Cultures
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DOI: 10.3389/fonc.2022.864723
Abstract: Patient-derived prostate tissue explant cultures are powerful research tools that offer the potential for personalized medicine. These cultures preserve the local microenvironment of the surrounding stroma but are not without limitations and challenges. There are… read more here.
Keywords: tissue slice; utility; prostate tissue; tissue ... See more keywords
Glioblastoma Tissue Slice Tandem-Cultures for Quantitative Evaluation of Inhibitory Effects on Invasion and Growth
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DOI: 10.3390/cancers12092707
Abstract: Simple Summary Glioblastomas are very malignant and essentially incurable brain tumors. One problem is the extensive penetration of tumor cells into the adjacent normal brain tissue. Thus, the testing of novel drugs requires appropriate tumor… read more here.
Keywords: tissue slice; tissue; slice tandem; brain ... See more keywords
Recent advances in organotypic tissue slice cultures for anticancer drug development
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DOI: 10.7150/ijbs.78997
Abstract: Organotypic tissue slice culture is established from animal or patient tissues and cultivated in an in vitro ecosystem. This technique has made countless contributions to anticancer drug development due to the vast number of advantages,… read more here.
Keywords: anticancer drug; organotypic tissue; tissue slice; drug development ... See more keywords