Multiscale network analysis identifies potential receptors for SARS‐CoV‐2 and reveals their tissue‐specific and age‐dependent expression
Sign Up to like & getrecommendations! Published in 2023 at "FEBS Letters"
DOI: 10.1002/1873-3468.14613
Abstract: The coronavirus disease 2019 (COVID‐19) pandemic has affected tens of millions of individuals and caused hundreds of thousands of deaths worldwide. Here, we present a comprehensive, multiscale network analysis of the transcriptional response to the… read more here.
Keywords: age; tissue specific; specific age; network analysis ... See more keywords
Predicting genome‐wide tissue‐specific enhancers via combinatorial transcription factor genomic occupancy analysis
Sign Up to like & getrecommendations! Published in 2024 at "FEBS Letters"
DOI: 10.1002/1873-3468.15030
Abstract: Enhancers are non‐coding cis‐regulatory elements crucial for transcriptional regulation. Mutations in enhancers can disrupt gene regulation, leading to disease phenotypes. Identifying enhancers and their tissue‐specific activity is challenging due to their lack of stereotyped sequences.… read more here.
Keywords: genomic occupancy; transcription factor; factor genomic; tissue specific ... See more keywords
Aptamer‐Directed Bidirectional Modulation of Vascular Niches for Promoted Regeneration of Segmental Trachea Defect
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202409071
Abstract: The simultaneous regeneration of avascular cartilage ring and vascular connective tissue in one biomimetic tracheal substitute has remained a remarkable challenge in the clinical breakthrough of tissue‐engineered trachea for repairing segmental trachea defect. Herein, an… read more here.
Keywords: tissue specific; vascular niches; regeneration; trachea ... See more keywords
Medical Applications of Porous Biomaterials: Features of Porosity and Tissue‐Specific Implications for Biocompatibility
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202102087
Abstract: Porosity is an important material feature commonly employed in implants and tissue scaffolds. The presence of material voids permits the infiltration of cells, mechanical compliance, and outward diffusion of pharmaceutical agents. Various studies have confirmed… read more here.
Keywords: porous biomaterials; applications porous; medical applications; tissue specific ... See more keywords
Aorta Regulatory T Cells with a Tissue‐Specific Phenotype and Function Promote Tissue Repair through Tff1 in Abdominal Aortic Aneurysms
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202104338
Abstract: Abstract In addition to maintaining immune tolerance, Foxp3+ regulatory T cells (Tregs) perform specialized functions in tissue homeostasis and remodeling. However, whether Tregs in aortic aneurysms have a tissue‐specific phenotype and function is unclear. Here,… read more here.
Keywords: phenotype function; phenotype; specific phenotype; tissue specific ... See more keywords
Functional Trachea Reconstruction Using 3D‐Bioprinted Native‐Like Tissue Architecture Based on Designable Tissue‐Specific Bioinks
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202202181
Abstract: Functional segmental trachea reconstruction remains a remarkable challenge in the clinic. To date, functional trachea regeneration with alternant cartilage‐fibrous tissue‐mimetic structure similar to that of the native trachea relying on the three‐dimensional (3D) bioprinting technology… read more here.
Keywords: specific bioinks; tissue specific; trachea reconstruction; tissue ... See more keywords
Unraveling Tissue‐Specific Fatty Acid Biosynthesis and Inter‐Tissue Crosstalk in Mice through Stable‐Isotope Tracing Metabolomics
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202503662
Abstract: Biosynthesis of free fatty acids (FFAs) in mammals is pivotal for metabolic homeostasis, yet a comprehensive understanding of tissue‐specific biosynthesis and inter‐tissue crosstalk of FFAs remains incomplete. In vivo stable‐isotope tracing metabolomics is utilized to… read more here.
Keywords: inter tissue; tissue crosstalk; biosynthesis; tissue specific ... See more keywords
Induction of Tyrosine Hydroxylase Gene Expression in Embryonal Carcinoma Stem Cells Using a Natural Tissue‐Specific Inducer
Sign Up to like & getrecommendations! Published in 2019 at "Developmental Neurobiology"
DOI: 10.1002/dneu.22703
Abstract: A large number of studies have focused on the generation of dopaminergic neurons from pluripotent cells. Differentiation of stem cells into distinct cell types is influenced by tissue‐specific microenvironment. Since, central nervous system undergoes further… read more here.
Keywords: tissue specific; embryonal carcinoma; carcinoma stem; stem ... See more keywords
Tissue-specific antigen-presenting cells contribute to distinct phenotypes of allergy.
Sign Up to like & getrecommendations! Published in 2023 at "European journal of immunology"
DOI: 10.1002/eji.202249980
Abstract: Antigen presenting cells (APCs) are critical cells bridging innate and adaptive immune responses by taking up, processing, and presenting antigens to naïve T cells. At steady state, APCs thus control both tissue homeostasis and the… read more here.
Keywords: antigen presenting; presenting cells; specific antigen; tissue specific ... See more keywords
Functional MRI registration with tissue‐specific patch‐based functional correlation tensors
Sign Up to like & getrecommendations! Published in 2018 at "Human Brain Mapping"
DOI: 10.1002/hbm.24021
Abstract: Population studies of brain function with resting‐state functional magnetic resonance imaging (rs‐fMRI) rely on accurate intersubject registration of functional areas. This is typically achieved through registration using high‐resolution structural images with more spatial details and… read more here.
Keywords: tissue specific; tissue; correlation; specific patch ... See more keywords
A group of tissue‐specific microRNAs contribute to the silencing of CUX1 in different cell lineages during development
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26852
Abstract: Cut‐like homeobox 1 (CUX1) is a highly conserved homeoprotein that functions as a transcriptional repressor of genes specifying terminal differentiation. We previously showed that liver‐specific microRNA‐122 (miR‐122) regulates the timing of liver development by silencing… read more here.
Keywords: cell lineages; tissue specific; cux1; different cell ... See more keywords