Acid-Directed Electrostatic Self-Assembly Generates Charge-Reversible Bacteria for Enhanced Tumor Targeting and Low Tissue Trapping.
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DOI: 10.1021/acsami.2c08684
Abstract: Despite recent preclinical progress with oncolytic bacteria in cancer therapy, dose-limiting toxicity has been a long-standing challenge for clinical application. Genetic and chemical modifications for enhancing the bacterial tumor-targeting ability have been unable to establish… read more here.
Keywords: self assembly; tumor targeting; tissue trapping; low tissue ... See more keywords