The NR4A agonist, Cytosporone B, attenuates pro-inflammatory mediators in human colorectal cancer tissue ex vivo.
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DOI: 10.1016/j.bbrc.2021.03.110
Abstract: Inflammation is a pivotal pathological factor in colorectal cancer (CRC) initiation and progression, and modulating this inflammatory state has the potential to ameliorate disease progression. NR4A receptors have emerged as key regulators of inflammatory pathways… read more here.
Keywords: agonist cytosporone; colorectal cancer; tissue; tissue vivo ... See more keywords