RBM20, a Therapeutic Target to Alleviate Myocardial Stiffness via Titin Isoforms Switching in HFpEF
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DOI: 10.3389/fcvm.2022.928244
Abstract: Increased myocardial stiffness is critically involved in heart diseases with impaired cardiac compliance, especially heart failure with preserved ejection fraction (HFpEF). Myocardial stiffness mainly derives from cardiomyocyte- and extracellular matrix (ECM)-derived passive stiffness. Titin, a… read more here.
Keywords: rbm20; stiffness; myocardial stiffness; titin isoforms ... See more keywords