The Drug Titration Paradox: Correlation of More Drug With Less Effect in Clinical Data
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Pharmacology and Therapeutics"
DOI: 10.1002/cpt.2162
Abstract: While analyzing clinical data where an anesthetic was titrated based on an objective measure of drug effect, we observed paradoxically that greater effect was associated with lesser dose. With this study we sought to find… read more here.
Keywords: titration paradox; titration; effect; drug ... See more keywords
The drug titration paradox: something obvious finally understood.
Sign Up to like & getrecommendations! Published in 2022 at "British journal of anaesthesia"
DOI: 10.1016/j.bja.2022.03.007
Abstract: The drug titration paradox is an emerging concept in clinical pharmacology. The paradox refers to the observation that when drug is titrated to a specified level of effect in a population of patients, the expected… read more here.
Keywords: drug; drug titration; titration paradox; paradox something ... See more keywords