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Published in 2020 at "Journal of Pharmaceutical Innovation"
DOI: 10.1007/s12247-020-09447-z
Abstract: Purpose Tizanidine (TZN) is used for the management of muscle spasms. Oral TZN is liable to first-pass metabolism and interindividual variation. Transdermal drug delivery systems (TDDS) are gaining research attention as an alternative route. The…
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Keywords:
bioanalytical comparison;
delivery;
tizanidine;
drug ... See more keywords
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Published in 2023 at "Journal of microencapsulation"
DOI: 10.1080/02652048.2023.2209651
Abstract: Tizanidine HCl (TH) is used as first-line therapy for the treatment of muscular spasm. The intranasal cubosomal delivery system of TH for site-specific delivery i.e. CNS was developed. Cubosomes of TH were prepared using Glyceryl…
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Keywords:
intranasal spray;
vivo;
brain;
spray cubosomal ... See more keywords