Articles with "tizanidine" as a keyword



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Bioanalytical Comparison of Transdermal Delivery of Tizanidine from Different Nanovesicular Carriers

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Published in 2020 at "Journal of Pharmaceutical Innovation"

DOI: 10.1007/s12247-020-09447-z

Abstract: Purpose Tizanidine (TZN) is used for the management of muscle spasms. Oral TZN is liable to first-pass metabolism and interindividual variation. Transdermal drug delivery systems (TDDS) are gaining research attention as an alternative route. The… read more here.

Keywords: bioanalytical comparison; delivery; tizanidine; drug ... See more keywords
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Intranasal spray of cubosomal Tizanidine Hydrochloride for brain targeting: In-vitro and in-vivo characterization.

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Published in 2023 at "Journal of microencapsulation"

DOI: 10.1080/02652048.2023.2209651

Abstract: Tizanidine HCl (TH) is used as first-line therapy for the treatment of muscular spasm. The intranasal cubosomal delivery system of TH for site-specific delivery i.e. CNS was developed. Cubosomes of TH were prepared using Glyceryl… read more here.

Keywords: intranasal spray; vivo; brain; spray cubosomal ... See more keywords