Differential Recognition of Computationally Optimized H3 Hemagglutinin Influenza Vaccine Candidates by Human Antibodies
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DOI: 10.1128/jvi.00896-22
Abstract: Vaccine development for circulating influenza viruses, particularly for the H3N2 subtype, remains challenging due to consistent antigenic drift. Computationally optimized broadly reactive antigen (COBRA) technology has proven effective for broadening influenza hemagglutinin (HA)-elicited antibody responses… read more here.
Keywords: recognition; computationally optimized; hemagglutinin; tj5 ... See more keywords