Activity of EGFR Tyrosine Kinase Inhibitors in NSCLC With Refractory Leptomeningeal Metastases
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DOI: 10.1016/j.jtho.2019.05.007
Abstract: Abstract Introduction Leptomeningeal metastases (LMs) are associated with dismal prognosis in NSCLC. Optimal management remains unknown in patients with EGFR-mutated NSCLC after initial tyrosine kinase inhibitor (TKI) failure. Methods We conducted a multicenter retrospective study… read more here.
Keywords: tyrosine kinase; leptomeningeal metastases; failure; clinical benefit ... See more keywords