Articles with "tks5" as a keyword



Crosstalk between invadopodia and the extracellular matrix.

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Published in 2020 at "European journal of cell biology"

DOI: 10.1016/j.ejcb.2020.151122

Abstract: The scaffold protein Tks5α is required for invadopodia-mediated cancer invasion both in vitro and in vivo. We have previously also revealed a role for Tks5 in tumor cell growth using three-dimensional (3D) culture model systems… read more here.

Keywords: tks5; crosstalk invadopodia; extracellular matrix; matrix ... See more keywords

The oncolytic avian reovirus p17 protein suppresses invadopodia formation via disruption of TKs5 complexes and oncogenic signaling pathways

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Published in 2025 at "Frontiers in Cellular and Infection Microbiology"

DOI: 10.3389/fcimb.2025.1603124

Abstract: Background Avian reovirus (ARV) is an oncolytic virus that induces autophagy and apoptosis in cancer cells, modulates the immune response, and exposes tumor-associated antigens to the immune system, making it a promising candidate for cancer… read more here.

Keywords: cancer; rab40b; invadopodia formation; tks5 ... See more keywords

The Role of TKS5 in Chromosome Stability and Bladder Cancer Progression

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms232214283

Abstract: TKS5 promotes invasion and migration through the formation of invadopodia in some tumour cells, and it also has an important physiological function in cell migration through podosome formation in various nontumour cells. To date, the… read more here.

Keywords: tks5; cell; role; migration ... See more keywords