TLK1‐mediated MK5‐S354 phosphorylation drives prostate cancer cell motility and may signify distinct pathologies
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DOI: 10.1002/1878-0261.13183
Abstract: Metastases account for the majority of prostate cancer (PCa) deaths, and targeting them is a major goal of systemic therapy. We identified a novel interaction between two kinases: tousled‐like kinase 1 (TLK1) and MAP kinase‐activated… read more here.
Keywords: tlk1 mk5; prostate cancer; mk5; motility ... See more keywords
The TLK1–MK5 Axis Regulates Motility, Invasion, and Metastasis of Prostate Cancer Cells
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DOI: 10.3390/cancers14235728
Abstract: Background Metastatic dissemination of prostate cancer (PCa) accounts for majority of PCa related deaths. However, the exact mechanism of PCa cell spread is still unknown. We uncovered a novel interaction between two unrelated promotility factors,… read more here.
Keywords: metastasis; tlk1 mk5; mk5; pca ... See more keywords