Cyclic AMP in human preterm infant blood is associated with increased TLR-mediated production of acute-phase and anti-inflammatory cytokines in vitro
Sign Up to like & getrecommendations! Published in 2019 at "Pediatric research"
DOI: 10.1038/s41390-019-0586-2
Abstract: BackgroundPreterm infants are at high risk of infection and have distinct pathogen recognition responses. Suggested mechanisms include soluble mediators that enhance cellular levels of cAMP. The aim of this study was to assess the relationship… read more here.
Keywords: production; preterm; mediated production; blood ... See more keywords
Premature neonatal gut microbial community patterns supporting an epithelial TLR-mediated pathway for necrotizing enterocolitis
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DOI: 10.1186/s12866-021-02285-0
Abstract: Background Necrotising enterocolitis (NEC) is a devastating bowel disease, primarily affecting premature infants, with a poorly understood aetiology. Prior studies have found associations in different cases with an overabundance of particular elements of the faecal… read more here.
Keywords: microbial community; community patterns; community; tlr mediated ... See more keywords
Interleukin-10 and prostaglandin E2 have complementary but distinct suppressive effects on Toll-like receptor-mediated dendritic cell activation in ovarian carcinoma
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DOI: 10.1371/journal.pone.0175712
Abstract: Dendritic cells (DC) have the potential to instigate a tumour-specific immune response, but their ability to prime naïve lymphocytes depends on their activation status. Thus, for tumour immunotherapy to be effective, the provision of appropriate… read more here.
Keywords: toll like; like receptor; tlr; activation ... See more keywords
A Simplified Herbal Formula Improves Cardiac Function and Reduces Inflammation in Mice Through the TLR-Mediated NF-κB Signaling Pathway
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DOI: 10.3389/fphar.2022.865614
Abstract: Nuanxinkang tablet (NXK), a Chinese herbal formula, can improve heart function and quality of life in patients with chronic heart failure (CHF). However, the mechanisms of action of NXK are not fully understood. In this… read more here.
Keywords: inflammation; function; cardiac function; mediated signaling ... See more keywords