Requirement of glycosylation machinery in TLR responses revealed by CRISPR/Cas9 screening
Sign Up to like & getrecommendations! Published in 2017 at "International Immunology"
DOI: 10.1093/intimm/dxx044
Abstract: The Toll family of receptors sense microbial products and activate a defense response. The molecular machinery required for the TLR response is not yet fully understood. In the present study, we used a clustered, regularly… read more here.
Keywords: cas9 screening; response; machinery; crispr cas9 ... See more keywords
TLR Responses in Preterm and Term Infant Cord Blood Mononuclear Cells
Sign Up to like & getrecommendations! Published in 2023 at "Pathogens"
DOI: 10.3390/pathogens12040596
Abstract: Preterm infants are more susceptible to severe bacterial and viral infectious diseases than their full-term counterparts. A major contributor to this increased susceptibility may be due to differences in their ability to respond to pathogens.… read more here.
Keywords: tlr responses; preterm term; term; stimulation ... See more keywords