Articles with "tlr2" as a keyword



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Identification of TLR2/4‐mediated phagocytosis and immune response activation pathways by vacuoles isolated from Saccharomyces cerevisiae

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Published in 2022 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.30342

Abstract: The vacuoles of the yeast Saccharomyces cerevisiae are closely related to mammalian lysosomes and play a role in macromolecular degradation due to the hydrolytic enzymes present inside. The vacuoles also regulate osmotic pressure and control… read more here.

Keywords: immune response; vacuoles isolated; tlr2; immune ... See more keywords
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The long noncoding RNA XIST regulates cardiac hypertrophy by targeting miR‐101

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Published in 2019 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.28047

Abstract: Cardiac hypertrophy and its resultant heart failure are among the most common causes of mortality, worldwide. Long noncoding RNAs (lncRNAs) are involved in diverse biological processes, and their vital role in the regulation of cardiac… read more here.

Keywords: cardiac hypertrophy; long noncoding; mir 101; tlr2 ... See more keywords
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Early Post-ischemic Brain Glucose Metabolism Is Dependent on Function of TLR2: a Study Using [18F]F-FDG PET-CT in a Mouse Model of Cardiac Arrest and Cardiopulmonary Resuscitation

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Published in 2021 at "Molecular Imaging and Biology"

DOI: 10.1007/s11307-021-01677-y

Abstract: The mammalian brain glucose metabolism is tightly and sensitively regulated. An ischemic brain injury caused by cardiac arrest (CA) and cardiopulmonary resuscitation (CPR) affects cerebral function and presumably also glucose metabolism. The majority of patients… read more here.

Keywords: pet; tlr2; glucose metabolism; 18f fdg ... See more keywords
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Forkhead box-P3+ regulatory T cells and toll-like receptor 2 co-expression in oral squamous cell carcinoma.

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Published in 2017 at "Acta histochemica"

DOI: 10.1016/j.acthis.2016.12.005

Abstract: BACKGROUND The function of forkhead box-P3 (FoxP3) regulatory T cells (Treg) and toll-like receptor (TLR)2 protein in the oral cancer microenvironment is not fully understood, but evidence from other malignancies suggests it is likely they… read more here.

Keywords: toll like; tlr2; forkhead box; regulatory cells ... See more keywords
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Leukocytic toll-like receptor 2 knockout protects against diabetes-induced cardiac dysfunction.

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Published in 2018 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2018.10.082

Abstract: Diabetic cardiomyopathy is characterized by the deterioration of the myocardial function. Emerging evidences have indicated that leukocytic toll-like receptor 2 (TLR2) played an important role in the development of diabetic cardiomyopathy. Our study aimed to… read more here.

Keywords: toll like; tlr2; like receptor; leukocytic toll ... See more keywords
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Human Adaptive Immunity Rescues an Inborn Error of Innate Immunity

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Published in 2017 at "Cell"

DOI: 10.1016/j.cell.2017.01.039

Abstract: The molecular basis of the incomplete penetrance of monogenic disorders is unclear. We describe here eight related individuals with autosomal recessive TIRAP deficiency. Life-threatening staphylococcal disease occurred during childhood in the proband, but not in… read more here.

Keywords: immunity; tlr2; tirap; anti lta ... See more keywords
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Microbial Exposure Enhances Immunity to Pathogens Recognized by TLR2 but Increases Susceptibility to Cytokine Storm through TLR4 Sensitization.

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Published in 2019 at "Cell reports"

DOI: 10.1016/j.celrep.2019.07.028

Abstract: Microbial exposures can define an individual's basal immune state. Cohousing specific pathogen-free (SPF) mice with pet store mice, which harbor numerous infectious microbes, results in global changes to the immune system, including increased circulating phagocytes and… read more here.

Keywords: response; tlr2; cytokine storm; mice ... See more keywords
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TLR2 contributes to trigger immune response of pleural mesothelial cells against Mycobacterium bovis BCG and M. tuberculosis infection

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Published in 2017 at "Cytokine"

DOI: 10.1016/j.cyto.2017.02.021

Abstract: HighlightsM. tuberculosis induces cytokines and chemokines production in PMCs via TLR2.M. tuberculosis activates NF‐&kgr;B and MAPKs in PMCs via TLR2 signaling.TLR2 is essential for iNOS expression in M. tuberculosis‐infected PMCs.TLR2 is critical for expression of… read more here.

Keywords: tlr2; infection; mesothelial cells; pmcs ... See more keywords
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Association of TLR2 gene polymorphisms with presumed viral-induced anterior uveitis in male Han Chinese.

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Published in 2019 at "Experimental eye research"

DOI: 10.1016/j.exer.2019.107777

Abstract: The purpose of this study was to investigate whether single nucleotide polymorphisms (SNPs) of TLR2, TLR3, TLR4 and TLR9 genes are associated with susceptibility to presumed viral-induced anterior uveitis (PVIAU) and Posner-Schlossman syndrome (PSS). A… read more here.

Keywords: tlr2; anterior uveitis; induced anterior; tlr2 gene ... See more keywords
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Melatonin mediated Foxp3‐downregulation decreases cytokines production via the TLR2 and TLR4 pathways in H. pylori infected mice

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Published in 2018 at "International Immunopharmacology"

DOI: 10.1016/j.intimp.2018.08.034

Abstract: ABSTRACT Melatonin has important immuno‐regulatory effects in inflammatory disorders but its specific role in Helicobacter pylori induced gastritis remains unclear. The aim of our study was to analyze the activity of melatonin against H. pylori… read more here.

Keywords: tlr2; treatment; infected mice; mice ... See more keywords

Activation of microglia and macrophages in the circumventricular organs of the mouse brain during TLR2-induced fever and sickness responses

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Published in 2019 at "Journal of Neuroimmunology"

DOI: 10.1016/j.jneuroim.2019.576973

Abstract: Toll-like receptor 2 (TLR2) recognizes cell wall components from Gram-positive bacteria. Until now, however, little has been known about the significance of brain TLR2 in controlling inflammation and thermoregulatory responses during systemic Gram-positive bacterial infection.… read more here.

Keywords: microglia macrophages; brain tlr2; induced fever; tlr2 ... See more keywords