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Published in 2022 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.30342
Abstract: The vacuoles of the yeast Saccharomyces cerevisiae are closely related to mammalian lysosomes and play a role in macromolecular degradation due to the hydrolytic enzymes present inside. The vacuoles also regulate osmotic pressure and control…
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Keywords:
immune response;
vacuoles isolated;
tlr2;
immune ... See more keywords
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Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28047
Abstract: Cardiac hypertrophy and its resultant heart failure are among the most common causes of mortality, worldwide. Long noncoding RNAs (lncRNAs) are involved in diverse biological processes, and their vital role in the regulation of cardiac…
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Keywords:
cardiac hypertrophy;
long noncoding;
mir 101;
tlr2 ... See more keywords
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Published in 2021 at "Molecular Imaging and Biology"
DOI: 10.1007/s11307-021-01677-y
Abstract: The mammalian brain glucose metabolism is tightly and sensitively regulated. An ischemic brain injury caused by cardiac arrest (CA) and cardiopulmonary resuscitation (CPR) affects cerebral function and presumably also glucose metabolism. The majority of patients…
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Keywords:
pet;
tlr2;
glucose metabolism;
18f fdg ... See more keywords
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Published in 2017 at "Acta histochemica"
DOI: 10.1016/j.acthis.2016.12.005
Abstract: BACKGROUND The function of forkhead box-P3 (FoxP3) regulatory T cells (Treg) and toll-like receptor (TLR)2 protein in the oral cancer microenvironment is not fully understood, but evidence from other malignancies suggests it is likely they…
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Keywords:
toll like;
tlr2;
forkhead box;
regulatory cells ... See more keywords
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Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.10.082
Abstract: Diabetic cardiomyopathy is characterized by the deterioration of the myocardial function. Emerging evidences have indicated that leukocytic toll-like receptor 2 (TLR2) played an important role in the development of diabetic cardiomyopathy. Our study aimed to…
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Keywords:
toll like;
tlr2;
like receptor;
leukocytic toll ... See more keywords
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Published in 2017 at "Cell"
DOI: 10.1016/j.cell.2017.01.039
Abstract: The molecular basis of the incomplete penetrance of monogenic disorders is unclear. We describe here eight related individuals with autosomal recessive TIRAP deficiency. Life-threatening staphylococcal disease occurred during childhood in the proband, but not in…
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Keywords:
immunity;
tlr2;
tirap;
anti lta ... See more keywords
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Published in 2019 at "Cell reports"
DOI: 10.1016/j.celrep.2019.07.028
Abstract: Microbial exposures can define an individual's basal immune state. Cohousing specific pathogen-free (SPF) mice with pet store mice, which harbor numerous infectious microbes, results in global changes to the immune system, including increased circulating phagocytes and…
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Keywords:
response;
tlr2;
cytokine storm;
mice ... See more keywords
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Published in 2017 at "Cytokine"
DOI: 10.1016/j.cyto.2017.02.021
Abstract: HighlightsM. tuberculosis induces cytokines and chemokines production in PMCs via TLR2.M. tuberculosis activates NF‐&kgr;B and MAPKs in PMCs via TLR2 signaling.TLR2 is essential for iNOS expression in M. tuberculosis‐infected PMCs.TLR2 is critical for expression of…
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Keywords:
tlr2;
infection;
mesothelial cells;
pmcs ... See more keywords
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Published in 2019 at "Experimental eye research"
DOI: 10.1016/j.exer.2019.107777
Abstract: The purpose of this study was to investigate whether single nucleotide polymorphisms (SNPs) of TLR2, TLR3, TLR4 and TLR9 genes are associated with susceptibility to presumed viral-induced anterior uveitis (PVIAU) and Posner-Schlossman syndrome (PSS). A…
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Keywords:
tlr2;
anterior uveitis;
induced anterior;
tlr2 gene ... See more keywords
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Published in 2018 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2018.08.034
Abstract: ABSTRACT Melatonin has important immuno‐regulatory effects in inflammatory disorders but its specific role in Helicobacter pylori induced gastritis remains unclear. The aim of our study was to analyze the activity of melatonin against H. pylori…
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Keywords:
tlr2;
treatment;
infected mice;
mice ... See more keywords
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Published in 2019 at "Journal of Neuroimmunology"
DOI: 10.1016/j.jneuroim.2019.576973
Abstract: Toll-like receptor 2 (TLR2) recognizes cell wall components from Gram-positive bacteria. Until now, however, little has been known about the significance of brain TLR2 in controlling inflammation and thermoregulatory responses during systemic Gram-positive bacterial infection.…
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Keywords:
microglia macrophages;
brain tlr2;
induced fever;
tlr2 ... See more keywords