Hepatocytes paradoxically affect intrahepatic IFN-γ production in autoimmune hepatitis due to Gal-9 expression and TLR2/4 ligand release.
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DOI: 10.1016/j.molimm.2020.05.014
Abstract: Hepatocytes are the targets in autoimmune hepatitis (AIH) that results in T cell-dependent liver injury. However, hepatocytes may also affect the hepatic T cells in AIH, but the underlying mechanisms are not fully understood. Here… read more here.
Keywords: intrahepatic ifn; tlr2 ligands; production; tlr2 ... See more keywords