Neonatal porcine blood derived dendritic cell subsets show activation after TLR2 or TLR9 stimulation
Sign Up to like & getrecommendations! Published in 2018 at "Developmental and Comparative Immunology"
DOI: 10.1016/j.dci.2018.03.012
Abstract: &NA; The present study investigated the innate immune response in vitro to determine porcine neonate responses with Toll‐like receptor (TLR)2 ligand (Pam3Cys) or TLR9 ligand (CpG) and compared these with adults. We identified the same… read more here.
Keywords: tlr2 tlr9; cell subsets; porcine; tlr9 stimulation ... See more keywords
NPT1220-312, a TLR2/TLR9 Small Molecule Antagonist, Inhibits Pro-Inflammatory Signaling, Cytokine Release, and NLRP3 Inflammasome Activation
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Inflammation"
DOI: 10.1155/2022/2337363
Abstract: Toll-like receptors (TLRs) play a critical role in innate immune system responses to damage-associated molecular patterns (DAMPs) and pathogen-associated molecular patterns (PAMPs). A growing body of evidence suggests that excessive TLR-mediated innate immune system activation… read more here.
Keywords: inflammatory signaling; tlr2 tlr9; release; pro inflammatory ... See more keywords