TLR8 combined withTLR3 or TLR4 agonists enhances DC-NK driven effector Tc1 cells.
Sign Up to like & getrecommendations! Published in 2018 at "Immunology letters"
DOI: 10.1016/j.imlet.2017.10.015
Abstract: BACKGROUND Most current prophylactic vaccines confer protection primarily through humoral immunity. Indeed, aluminum salts which have been widely used as adjuvants in vaccines primarily enhance Th2-driven antibody responses. Therefore, new vaccines formulation is moving toward… read more here.
Keywords: tlr3 tlr4; tlr agonists; effector cells; tc1 cells ... See more keywords
The differences in immunoadjuvant mechanisms of TLR3 and TLR4 agonists on the level of antigen-presenting cells during immunization with recombinant adenovirus vector
Sign Up to like & getrecommendations! Published in 2018 at "BMC Immunology"
DOI: 10.1186/s12865-018-0264-x
Abstract: BackgroundAgonists of TLR3 and TLR4 are effective immunoadjuvants for different types of vaccines. The mechanisms of their immunostimulatory action differ significantly; these differences are particularly critical for immunization with non-replicating adenovirus vectors (rAds) based vaccines.… read more here.
Keywords: presenting cells; tlr3 tlr4; agonists level; tlr4 agonists ... See more keywords
Toll-Like Receptors Serve as Biomarkers for Early Diagnosis and Prognosis Assessment of Kidney Renal Clear Cell Carcinoma by Influencing the Immune Microenvironment: Comprehensive Bioinformatics Analysis Combined With Experimental Validation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.832238
Abstract: Background: Toll-like receptors (TLRs) are important initiators of innate and acquired immune responses. However, its role in kidney renal clear cell carcinoma (KIRC) remains unclear. Methods: TLRs and their relationships with KIRC were studied in… read more here.
Keywords: toll like; tlr3 tlr4; kidney renal; analysis ... See more keywords