Leptin alleviated ovarian ischemia-reperfusion injury in rats via modulation of Sirt-1/Nrf2 and TLR4/NF-kB/caspase-3 signaling pathways
Sign Up to like & getrecommendations! Published in 2023 at "Endocrine Regulations"
DOI: 10.2478/enr-2023-0004
Abstract: Abstract Objective. Ovarian torsion is a gynecological emergency that occurs mostly during the female reproductive years due to ovarian masses or surgical manipulation. This work aims to explore the probable protective effect of leptin on… read more here.
Keywords: reperfusion injury; group; tlr4 caspase; ischemia reperfusion ... See more keywords
Lipopolysaccharide Recognition in the Crossroads of TLR4 and Caspase-4/11 Mediated Inflammatory Pathways
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.585146
Abstract: The innate immune response to lipopolysaccharide is essential for host defense against Gram-negative bacteria. In response to bacterial infection, the TLR4/MD-2 complex that is expressed on the surface of macrophages, monocytes, dendritic, and epithelial cells… read more here.
Keywords: tlr4 caspase; caspase; caspase mediated; tlr4 complex ... See more keywords