Intestinal toll-like receptor 4 knockout alters the functional capacity of the gut microbiome following irinotecan treatment
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DOI: 10.1007/s00280-021-04382-3
Abstract: Irinotecan can cause high levels of diarrhea caused by toxic injury to the gastrointestinal microenvironment. Toll-like receptor 4 (TLR4) and the gut microbiome have previously been implicated in gastrointestinal toxicity and diarrhea; however, the link… read more here.
Keywords: tlr4 iec; tlr4; irinotecan treatment; microbiome ... See more keywords