TLR4 inhibition ameliorates mesencephalic substantia nigra injury in neonatal rats exposed to lipopolysaccharide via regulation of neuro-immunity
Sign Up to like & getrecommendations! Published in 2020 at "Brain Research Bulletin"
DOI: 10.1016/j.brainresbull.2020.09.012
Abstract: Dopaminergic neurons play a key role in motor function of the extrapyramidal system. Previous studies have shown that septic neonates may have cognitive dysfunction in later life. Toll-like receptor 4 (TLR4) is a transmembrane protein… read more here.
Keywords: exposed lipopolysaccharide; inhibition; rats exposed; dopaminergic neurons ... See more keywords
TLR4 inhibition suppresses growth in oestrogen-induced prolactinoma models.
Sign Up to like & getrecommendations! Published in 2022 at "Endocrine-related cancer"
DOI: 10.1530/erc-22-0168
Abstract: Prolactinomas have harmful effects on human health. Bromocriptine is the only commercially available drug in China, but about 25% of prolactinoma patients do not respond to it in clinic, its pathogenesis remains unknown. Thus, its… read more here.
Keywords: prolactinoma; estradiol; prl; expression ... See more keywords