Polygonatum sibiricum polysaccharides play anti-cancer effect through TLR4-MAPK/NF-κB signaling pathways.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2018.01.070
Abstract: OBJECTIVE To investigate the anti-cancer effect of Polygonatum sibiricum polysaccharides (PSP) and the underlying mechanism. METHODS Tumor-bearing mice were randomly divided into normal saline (NS) group, adriamycin (ADM) group, PSP group and lipopolysaccharide (LPS) group.… read more here.
Keywords: signaling pathways; tlr4 mapk; group; effect ... See more keywords
Catalpol Alleviates Depression by Inhibiting NLRP3 Inflammasome via TLR4/MAPK/NF-Κb Pathway
Sign Up to like & getrecommendations! Published in 2023 at "Iranian Journal of Public Health"
DOI: 10.18502/ijph.v52i4.12440
Abstract: Background: We aimed to explore catalpol and NF-k. The role of antidepressant and anti-inflammatory effects of b inhibitor in depression induced by chronic unpredictable mild stress (CUMS). Methods: Under the guidance of Qiqihar Medical University,… read more here.
Keywords: depression; level; model; tlr4 mapk ... See more keywords