Network pharmacology and molecular docking analysis on the mechanism of Cordyceps militaris polysaccharide regulating immunity through TLR4/TNF-α pathwayss.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of biochemical and molecular toxicology"
DOI: 10.1002/jbt.23345
Abstract: The role of polysaccharide components in the immune system, especially immunomodulatory effects, has received increasing attention. In this context, in this study, network pharmacology was adopted to explore the hypothesis of a multitarget mechanism for… read more here.
Keywords: molecular docking; pharmacology; mechanism; network pharmacology ... See more keywords
LPS-TLR4/MD-2–TNF-α signaling mediates alcohol-induced liver fibrosis in rats
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Toxicologic Pathology"
DOI: 10.1293/tox.2021-0018
Abstract: Liver fibrosis results from liver inflammation and progresses to liver cirrhosis or liver cancer. It is known that nonalcoholic liver disease is mediated by the Toll-like receptor 4 (TLR4)/myeloid differentiation factor-2 (MD-2)–tumor necrosis factor-alpha (TNF-α)… read more here.
Keywords: tnf signaling; liver fibrosis; tlr4 tnf;
Evaluation of the protective role of resveratrol against sepsis caused by LPS via TLR4/NF-κB/TNF-α signaling pathways: Experimental study.
Sign Up to like & getrecommendations! Published in 2023 at "Cell biochemistry and function"
DOI: 10.2139/ssrn.4199195
Abstract: The development and progression of sepsis are multifactorial and influence the immunological, endocrine, and cardiovascular systems of the body. Our knowledge of the key mechanisms involved in the pathogenesis of sepsis has expanded exponentially, yet… read more here.
Keywords: sepsis; evaluation; resveratrol; study ... See more keywords