Preventive Effect of Lycopene in Dextran Sulfate Sodium-Induced Ulcerative Colitis Mice through the Regulation of TLR4/TRIF/NF-κB Signaling Pathway and Tight Junctions.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.1c05128
Abstract: The preventive effect and molecular mechanism of lycopene (LP) in dextran sulfate sodium (DSS)-induced ulcerative colitis (UC) in mice were evaluated. Compared to the DSS group, the LP prevention groups not only significantly inhibited the… read more here.
Keywords: preventive effect; dextran sulfate; effect; tlr4 trif ... See more keywords
Anti-inflammatory effects of nobiletin on TLR4/TRIF/IRF3 and TLR9/IRF7 signaling pathways in prostate cancer cells
Sign Up to like & getrecommendations! Published in 2020 at "Immunopharmacology and Immunotoxicology"
DOI: 10.1080/08923973.2020.1725040
Abstract: Abstract Background: Toll-like receptors (TLRs) are often expressed in natural immune cells as well as in tumor cells. TLR4 exhibits both tumor promoting and tumor-suppressing roles and higher TLR9 expression is an important marker of… read more here.
Keywords: irf3 tlr9; signaling pathways; tlr4 trif; pca ... See more keywords
Pathogenic Leptospires Limit Dendritic Cell Activation Through Avoidance of TLR4 and TRIF Signaling
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.911778
Abstract: Leptospira interrogans is a bacterial species responsible for leptospirosis, a neglected worldwide zoonosis. Mice and rats are resistant and can become asymptomatic carriers, whereas humans and some other mammals may develop severe forms of leptospirosis.… read more here.
Keywords: cell activation; tlr4; tlr4 trif; activation ... See more keywords
RP105 alleviates myocardial ischemia reperfusion injury via inhibiting TLR4/TRIF signaling pathways
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Molecular Medicine"
DOI: 10.3892/ijmm.2018.3538
Abstract: The Toll-like receptor 4 (TLR4) signal pathway-induced inflammation is considered to be a crucial link to myocardial ischemia reperfusion injury (MIRI). Our previous study proved that radioprotective 105 kDa protein (RP105), a negative regulator of… read more here.
Keywords: rp105; myocardial ischemia; reperfusion; tlr4 trif ... See more keywords