MiR‐150 alleviates neuropathic pain via inhibiting toll‐like receptor 5
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26269
Abstract: MicroRNAs (miRNAs) are reported as vital participators in the pathophysiological course of neuropathic pain. However, the underlying mechanisms of the functional roles of miRNAs in neuropathic pain are largely unknown. This study was designed to… read more here.
Keywords: toll like; like receptor; mir 150; neuropathic pain ... See more keywords
Extension and refinement of the recognition motif for Toll‐like receptor 5 activation by flagellin
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.3vma0118-035r
Abstract: TLRs sense conserved and essential molecular components of microbes that invade multicellular organisms. The wide range of TLR agonists, differing in size and shape, is recognized either through a single or a pair of binding… read more here.
Keywords: recognition; binding sites; receptor; flagellin ... See more keywords
Molecular cloning and functional studies on magang goose toll-like receptor 5.
Sign Up to like & getrecommendations! Published in 2021 at "Veterinary immunology and immunopathology"
DOI: 10.1016/j.vetimm.2021.110236
Abstract: Disease outbreaks heavily impact the economic viability of animal industries. Little is known about the mechanisms of immune system-related diseases in geese. Toll-like receptors (TLRs) play a major role in the anti-inflammatory immunity process in… read more here.
Keywords: toll like; magang goose; expression; toll ... See more keywords
T4SS-dependent TLR5 activation by Helicobacter pylori infection
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-13506-6
Abstract: Toll-like receptor TLR5 recognizes a conserved domain, termed D1, that is present in flagellins of several pathogenic bacteria but not in Helicobacter pylori. Highly virulent H. pylori strains possess a type IV secretion system (T4SS)… read more here.
Keywords: helicobacter pylori; pylori infection; tlr5; tlr5 activation ... See more keywords
Host species adaptation of TLR5 signalling and flagellin recognition
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-17935-5
Abstract: Toll-like receptor 5 (TLR5) recognition of flagellin instigates inflammatory signalling. Significant sequence variation in TLR5 exists between animal species but its impact on activity is less well understood. Building on our previous research that bovine… read more here.
Keywords: host species; bovine; recognition; tlr5 signalling ... See more keywords
TLR5 activation induces expression of the pro-inflammatory mediator Urokinase Plasminogen Activator via NF-κB and MAPK signalling pathways in human dental pulp cells.
Sign Up to like & getrecommendations! Published in 2019 at "International endodontic journal"
DOI: 10.1111/iej.13140
Abstract: AIM To explore the involvement of TLR5 in pulp inflammation and to examine the effects of TLR5 activation with its ligand, FlaB protein, on pro-inflammatory gene expression. METHODOLOGY TLR5 expression in dental pulp tissues and… read more here.
Keywords: tlr5 activation; signalling pathways; expression; dental pulp ... See more keywords
Fish TLR5 develops a taste for viral RNA
Sign Up to like & getrecommendations! Published in 2022 at "EMBO Reports"
DOI: 10.15252/embr.202255443
Abstract: These days not only humans but also freshwater fish battle with infections by RNA viruses (Zou & Nie, 2017). This observation prompted Liao et al to turn their attention to viral recognition in Grass carp (Ctenopharyngodon… read more here.
Keywords: freshwater fish; taste viral; fish tlr5; tlr5 ... See more keywords