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   Articles with "tlr5" as a keyword



MiR‐150 alleviates neuropathic pain via inhibiting toll‐like receptor 5

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recommendations! Published in 2018 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.26269

Abstract: MicroRNAs (miRNAs) are reported as vital participators in the pathophysiological course of neuropathic pain. However, the underlying mechanisms of the functional roles of miRNAs in neuropathic pain are largely unknown. This study was designed to… read more here.

Keywords: toll like; like receptor; mir 150; neuropathic pain ... See more keywords

Extension and refinement of the recognition motif for Toll‐like receptor 5 activation by flagellin

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recommendations! Published in 2018 at "Journal of Leukocyte Biology"

DOI: 10.1002/jlb.3vma0118-035r

Abstract: TLRs sense conserved and essential molecular components of microbes that invade multicellular organisms. The wide range of TLR agonists, differing in size and shape, is recognized either through a single or a pair of binding… read more here.

Keywords: recognition; binding sites; receptor; flagellin ... See more keywords

Molecular cloning and functional studies on magang goose toll-like receptor 5.

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recommendations! Published in 2021 at "Veterinary immunology and immunopathology"

DOI: 10.1016/j.vetimm.2021.110236

Abstract: Disease outbreaks heavily impact the economic viability of animal industries. Little is known about the mechanisms of immune system-related diseases in geese. Toll-like receptors (TLRs) play a major role in the anti-inflammatory immunity process in… read more here.

Keywords: toll like; magang goose; expression; toll ... See more keywords

T4SS-dependent TLR5 activation by Helicobacter pylori infection

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recommendations! Published in 2019 at "Nature Communications"

DOI: 10.1038/s41467-019-13506-6

Abstract: Toll-like receptor TLR5 recognizes a conserved domain, termed D1, that is present in flagellins of several pathogenic bacteria but not in Helicobacter pylori. Highly virulent H. pylori strains possess a type IV secretion system (T4SS)… read more here.

Keywords: helicobacter pylori; pylori infection; tlr5; tlr5 activation ... See more keywords

Host species adaptation of TLR5 signalling and flagellin recognition

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recommendations! Published in 2017 at "Scientific Reports"

DOI: 10.1038/s41598-017-17935-5

Abstract: Toll-like receptor 5 (TLR5) recognition of flagellin instigates inflammatory signalling. Significant sequence variation in TLR5 exists between animal species but its impact on activity is less well understood. Building on our previous research that bovine… read more here.

Keywords: host species; bovine; recognition; tlr5 signalling ... See more keywords

DOP27 Systemic antibody responses against gut microbiota flagellins implicate shared and divergent immune reactivity in Crohn's Disease and chronic fatigue syndrome

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recommendations! Published in 2024 at "Journal of Crohn's and Colitis"

DOI: 10.1093/ecco-jcc/jjad212.0067

Abstract: Patients with Crohn’s disease (CD) and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) exhibit elevated antibody responses against gut microbiota flagellins. However, flagellin-specific antibody repertoires and functional roles in the diseases remain incompletely understood. Bacterial flagellins can… read more here.

Keywords: tlr5; crohn disease; antibody; antibody responses ... See more keywords

P0180 Bifidobacterium longum alleviates dextran sulfate sodium-induced colitis through the differential regulation of Toll-like receptor 5 on enteric glial cells

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recommendations! Published in 2025 at "Journal of Crohn's and Colitis"

DOI: 10.1093/ecco-jcc/jjae190.0354

Abstract: Inflammatory bowel disease (IBD) is a chronic immune-associated disease arising from gastrointestinal dysbiosis and subsequent immunological dysfunction. Numerous studies have reported the beneficial effects of probiotics, such as Bifidobacterium longum (BL), on IBD, while the… read more here.

Keywords: tlr5; bifidobacterium longum; egc; gdnf ... See more keywords

TLR5 activation induces expression of the pro-inflammatory mediator Urokinase Plasminogen Activator via NF-κB and MAPK signalling pathways in human dental pulp cells.

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recommendations! Published in 2019 at "International endodontic journal"

DOI: 10.1111/iej.13140

Abstract: AIM To explore the involvement of TLR5 in pulp inflammation and to examine the effects of TLR5 activation with its ligand, FlaB protein, on pro-inflammatory gene expression. METHODOLOGY TLR5 expression in dental pulp tissues and… read more here.

Keywords: tlr5 activation; signalling pathways; expression; dental pulp ... See more keywords

Systemic antibody responses against gut microbiota flagellins implicate shared and divergent immune reactivity in Crohn’s disease and chronic fatigue syndrome

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recommendations! Published in 2024 at "Microbiome"

DOI: 10.1186/s40168-024-01858-1

Abstract: Background Elevated systemic antibody responses against gut microbiota flagellins are observed in both Crohn’s disease (CD) and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), suggesting potential serological biomarkers for diagnosis. However, flagellin-specific antibody repertoires and functional roles… read more here.

Keywords: tlr5; antibody; antibody responses; responses gut ... See more keywords

Fish TLR5 develops a taste for viral RNA

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recommendations! Published in 2022 at "EMBO Reports"

DOI: 10.15252/embr.202255443

Abstract: These days not only humans but also freshwater fish battle with infections by RNA viruses (Zou & Nie, 2017). This observation prompted Liao et al to turn their attention to viral recognition in Grass carp (Ctenopharyngodon… read more here.

Keywords: freshwater fish; taste viral; fish tlr5; tlr5 ... See more keywords

TLR5-deficiency controls dendritic cell subset development in an autoimmune diabetes-susceptible model

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recommendations! Published in 2024 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2024.1333967

Abstract: Introduction The incidence of the autoimmune disease, type 1 diabetes (T1D), has been increasing worldwide and recent studies have shown that the gut microbiota are associated with modulating susceptibility to T1D. Toll-like receptor 5 (TLR5)… read more here.

Keywords: tlr5; autoimmune diabetes; development autoimmune; tlr5 deficiency ... See more keywords