T4SS-dependent TLR5 activation by Helicobacter pylori infection
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-13506-6
Abstract: Toll-like receptor TLR5 recognizes a conserved domain, termed D1, that is present in flagellins of several pathogenic bacteria but not in Helicobacter pylori. Highly virulent H. pylori strains possess a type IV secretion system (T4SS)… read more here.
Keywords: helicobacter pylori; pylori infection; tlr5; tlr5 activation ... See more keywords
TLR5 activation induces expression of the pro-inflammatory mediator Urokinase Plasminogen Activator via NF-κB and MAPK signalling pathways in human dental pulp cells.
Sign Up to like & getrecommendations! Published in 2019 at "International endodontic journal"
DOI: 10.1111/iej.13140
Abstract: AIM To explore the involvement of TLR5 in pulp inflammation and to examine the effects of TLR5 activation with its ligand, FlaB protein, on pro-inflammatory gene expression. METHODOLOGY TLR5 expression in dental pulp tissues and… read more here.
Keywords: tlr5 activation; signalling pathways; expression; dental pulp ... See more keywords