Cyclophosphamide induced intestinal injury is alleviated by blocking the TLR9/caspase3/GSDME mediated intestinal epithelium pyroptosis.
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DOI: 10.2139/ssrn.4255218
Abstract: OBJECTIVES Cyclophosphamide (CYC) was commonly used to treat autoimmune disorders, and it could also cause side effects such as intestinal damage. This study aimed to explore the mechanism of CYC-induced intestinal cytotoxicity and provide evidence… read more here.
Keywords: induced intestinal; tlr9 caspase3; pyroptosis; gsdme ... See more keywords