Role of TLR9 in Oncogenic Virus-Produced Cancer
Sign Up to like & getrecommendations! Published in 2017 at "Viral Immunology"
DOI: 10.1089/vim.2016.0103
Abstract: Abstract Nucleic acid recognition by toll-like receptor 9 (TLR9) initiates signaling pathways that regulate the production of proinflammatory cytokines or type I interferons, as well as many other molecules required to initialize the immune response.… read more here.
Keywords: role tlr9; tlr9 expression; tlr9; recognition ... See more keywords
TLR9 expression in Chronic Lymphocytic Leukemia identifies a pro-migratory subpopulation and novel therapeutic target.
Sign Up to like & getrecommendations! Published in 2021 at "Blood"
DOI: 10.1182/blood.2020005964
Abstract: CLL remains incurable despite BCR-targeted inhibitors revolutionizing treatment. This suggests that other signaling molecules are involved in disease escape mechanisms and resistance. Toll-like receptor 9 (TLR9) is a promising candidate, which is activated by unmethylated… read more here.
Keywords: cll; dna; tlr9 expression; tlr9 ... See more keywords
High expression levels of TLR9 and PD-L1 indicates a poor prognosis in patients with angioimmunoblastic T-cell lymphoma: a retrospective study of 88 cases in a single center
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cancer"
DOI: 10.7150/jca.37033
Abstract: Background: The role of TLR9 expressed by tumor cells in evading immune surveillance was confirmed. PD-L1 expression in tumor cells plays a key role in tumor immune escape, which is associated with poor prognosis. However,… read more here.
Keywords: cell; poor prognosis; tlr9 expression; expression ... See more keywords