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Published in 2022 at "Science"
DOI: 10.1126/science.abf9419
Abstract: Description Tertiary lymphoid structures in cancer Tertiary lymphoid structures (TLSs) are lymphoid formations that are found in nonlymphoid tissues. TLS can develop in inflamed tissues and are associated with chronic inflammatory disorders, autoimmunity, and cancer.…
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Keywords:
cell;
lymphoid structures;
tertiary lymphoid;
formation ... See more keywords
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1
Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.868155
Abstract: Background Tertiary lymphoid structures (TLSs) have been proven to be predictive biomarkers of favorable clinical outcomes and response to immunotherapies in several solid malignancies. Nevertheless, the effect of TLSs in patients with breast cancer (BC)…
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Keywords:
presence;
tertiary lymphoid;
tls signature;
tlss ... See more keywords
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2
Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1096220
Abstract: Background The maturity and spatial distribution of tertiary lymphoid structures (TLSs) vary dynamically within and between cancers, leading to a controversial role in cancer. We aimed to develop a simple morphology-based approach to identify the…
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Keywords:
cell;
lymphoid structures;
tertiary lymphoid;
tlss ... See more keywords