Articles with "tlx591" as a keyword



177Lu-DOTA-TLX591 safety, biodistribution and dosimetry study (ProstACT-SELECT).

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Published in 2022 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2022.40.16_suppl.tps5109

Abstract: TPS5109 Background: The cell surface glycoprotein prostate-specific membrane antigen (PSMA) has proven to be an ideal therapeutic target in prostate cancer (PC) as it is highly expressed by malignant prostate cells.1,2 177Lu-DOTA-HuJ591-CHO (TLX591) is a… read more here.

Keywords: biodistribution dosimetry; tlx591; safety; 177lu dota ... See more keywords

Safety, tolerability, and dosimetry of 177Lu-TLX591 with best standard of care in patients with PSMA-expressing metastatic castration-resistant prostate cancer (ProstAct-SELECT).

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Published in 2024 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2024.42.4_suppl.tps253

Abstract: TPS253 Background: Prostate-specific membrane antigen (PSMA) has proven to be an ideal therapeutic target in prostate cancer (PC) as it is highly expressed by malignant prostate cells. Based on previous clinical evidence of its favorable… read more here.

Keywords: 177lu tlx591; prostate cancer; tlx591; safety ... See more keywords