Flurochloridone induces Sertoli cell apoptosis through ROS-dependent mitochondrial pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2021.112183
Abstract: Flurochloridone (FLC), a selective herbicide used on a global scale, has been reported to have male reproductive toxicity which underlying mechanism is still largely unknown. The present study was conducted to determine the effects of… read more here.
Keywords: apoptosis; sertoli cell; flurochloridone; tm4 ... See more keywords
T-2 Toxin Caused Mice Testicular Inflammation Injury via ROS-Mediated NLRP3 Inflammasome Activation.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c05317
Abstract: T-2 toxin treatment causes male reproduction system dysfunction, although the exact mechanism remains unclear. In this research, male Kunming mice and TM4 cells were treated with varying concentrations of the T-2 toxin for evaluating the… read more here.
Keywords: toxin caused; toxin; inflammasome activation; tm4 ... See more keywords
PM2.5 mediates mouse testis Sertoli TM4 cell damage by reducing cellular NAD.
Sign Up to like & getrecommendations! Published in 2023 at "Toxicology mechanisms and methods"
DOI: 10.1080/15376516.2023.2215862
Abstract: Objective: This study aims to explore the mechanism of PM2.5 damage to the reproductive system of male mice. Methods: Mouse testis Sertoli TM4 cells were divided into four groups: a control group (no additional ingredients… read more here.
Keywords: testis sertoli; sertoli tm4; mouse testis; pm2 ... See more keywords