Glass fiber reinforced and β‐nucleating agents regulated polypropylene: A complementary approach and a case study
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Applied Polymer Science"
DOI: 10.1002/app.45768
Abstract: A two-step process for preparing glass fibers (GFs) reinforced β-nucleated PP composites was designed and developed. The complementary approach combined GFs reinforcement and β-nucleating agents regulation using N,N′-dicyclohexyl-2,6-napthalene-dicarboxamide (TMB-5) in the presence of maleic anhydride… read more here.
Keywords: glass; complementary approach; mechanical properties; approach ... See more keywords
Tumor Mutation Burden as a Potential Biomarker for PD-1/PD-L1 Inhibition in Advanced Non-small Cell Lung Cancer
Sign Up to like & getrecommendations! Published in 2020 at "Targeted Oncology"
DOI: 10.1007/s11523-020-00703-3
Abstract: Background Immunotherapy based on programmed cell death protein 1 (PD-1)/programmed death-ligand 1 (PD-L1) inhibitors has revolutionized the treatment of non-small cell lung cancer (NSCLC). Patients with high PD-L1 expression or DNA mismatch repair deficiency (dMMR)/microsatellite… read more here.
Keywords: tmb; biomarker; group; cancer ... See more keywords
Genomic Features of Response to Combination Immunotherapy in Patients with Advanced Non-Small-Cell Lung Cancer
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Cell"
DOI: 10.1016/j.ccell.2018.03.018
Abstract: Summary Combination immune checkpoint blockade has demonstrated promising benefit in lung cancer, but predictors of response to combination therapy are unknown. Using whole-exome sequencing to examine non-small-cell lung cancer (NSCLC) treated with PD-1 plus CTLA-4… read more here.
Keywords: combination; tmb; response; lung cancer ... See more keywords
High-efficiency application of CTS-Co NPs mimicking peroxidase enzyme on TMB(ox).
Sign Up to like & getrecommendations! Published in 2021 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2021.133429
Abstract: In this study, analytical studies of Chitosan-Cobalt(II) (CTS-Co(II)) nanoparticles (CTS - Co NPs) by mimicking horseradish peroxidase (HRP) were evaluated. In the applications, it was observed that CTS-Co NPs 3,3' 5,5' tetramethylbenzidine (TMB) oxidized in… read more here.
Keywords: enzyme; peroxidase; nps mimicking; spectroscopy ... See more keywords
Ag–Cu@FA hydrogel-nanocomposites as catalyst and SERS substrate for the oxidation of TMB
Sign Up to like & getrecommendations! Published in 2020 at "Composites Communications"
DOI: 10.1016/j.coco.2020.100485
Abstract: Abstract Ag–Cu@FA hydrogel-nanocomposites were prepared by embedding copper nanoclusters (CuNCs) and silver nanoparticles (AgNPs) in the hydrogel matrix of folic acid (FA). This nanocomposites exhibited high catalytic activity for the oxidation of 3,3′,5,5′-tetramethylbenzidine (TMB) in… read more here.
Keywords: catalyst sers; oxidation; nanocomposites catalyst; hydrogel nanocomposites ... See more keywords
Interference of tumour mutational burden with outcome of patients with head and neck cancer treated with definitive chemoradiation: a multicentre retrospective study of the German Cancer Consortium Radiation Oncology Group.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of cancer"
DOI: 10.1016/j.ejca.2019.04.015
Abstract: BACKGROUND Tumour mutational burden (TMB) estimated from whole exome sequencing or comprehensive gene panels has previously been established as predictive factor of response to immune checkpoint inhibitors (ICIs). Its predictive value for the efficacy of concurrent… read more here.
Keywords: tmb; tumour mutational; cancer; gene ... See more keywords
Hot or Not: Tumor Mutational Burden (TMB) as a Biomarker of Immunotherapy Response in Genitourinary Cancers.
Sign Up to like & getrecommendations! Published in 2020 at "Urology"
DOI: 10.1016/j.urology.2020.10.030
Abstract: Pembrolizumab was recently approved for treatment of cancers with high tumor mutational burden (TMB). We conduct a focused literature review of TMB as a predictive biomarker. TMB quantifies the sum of non-synonymous coding mutations (typically… read more here.
Keywords: tumor mutational; biomarker; genitourinary cancers; tmb ... See more keywords
N-Doped Carbon Nanotubes Supported Fe-Mn Dual-Single-Atoms Nanozyme with Synergistically Enhanced Peroxidase Activity for Sensitive Colorimetric Detection of Acetylcholinesterase and Its Inhibitor.
Sign Up to like & getrecommendations! Published in 2023 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.3c01070
Abstract: Monitoring acetylcholinesterase (AChE) and its inhibitors is of importance for early diagnosis and therapy of neurological diseases. Herein, N-doped carbon nanotubes supported Fe-Mn dual-single-atoms (FeMn DSAs/N-CNTs) were fabricated by a simple pyrolysis, as thoroughly figured… read more here.
Keywords: single atoms; dual single; detection; activity ... See more keywords
Trimethyl Borate as Film-Forming Electrolyte Additive To Improve High-Voltage Performances.
Sign Up to like & getrecommendations! Published in 2019 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.9b03417
Abstract: Enhancing the stability of the interface between the electrode and electrolyte at high voltages is crucial concerning the development of Li-ion batteries with high energy densities. Application of some additives in the electrolyte is not… read more here.
Keywords: borate film; trimethyl borate; electrolyte; tmb ... See more keywords
A pan-cancer analysis of PD-L1 immunohistochemistry and gene amplification, tumor mutation burden and microsatellite instability in 48,782 cases
Sign Up to like & getrecommendations! Published in 2020 at "Modern Pathology"
DOI: 10.1038/s41379-020-00664-y
Abstract: PD-L1 immunohistochemistry (IHC) currently has the most Food and Drug Administration (FDA) approvals as a companion diagnostic (CDx) for immunotherapies in specific tumor types; however, multiple other immunotherapy biomarkers exist. We performed this study to… read more here.
Keywords: tmb; analysis; gene amplification; tumor ... See more keywords
bTMB is a promising predictive biomarker
Sign Up to like & getrecommendations! Published in 2019 at "Nature Reviews Clinical Oncology"
DOI: 10.1038/s41571-019-0202-8
Abstract: Nature reviews | CliniCal OnCOlOgy tumour mutational burden (tMB) is a promising biomarker of a response to immunecheckpoint inhibitors, independent of programmed cell death 1 ligand 1 (PDL1) status. tMB is usually measured in DNa… read more here.
Keywords: biomarker; tissue; cancer; tmb ... See more keywords