Articles with "tmb gep" as a keyword



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Genomic biomarkers in relation to PD-1 checkpoint blockade response.

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Published in 2018 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2018.36.5_suppl.25

Abstract: 25Background: Somatic tumor mutational burden (TMB) and a T-cell inflamed gene expression profile (GEP) predict response to anti-PD-1/PD-L1 immunotherapies in multiple tumor types. We assessed the potential for GEP and TMB to jointly predict clinical… read more here.

Keywords: gep low; response; genomic biomarkers; tmb ... See more keywords