TMBIM6/BI-1 contributes to cancer progression through assembly with mTORC2 and AKT activation
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-17802-4
Abstract: Transmembrane B cell lymphoma 2-associated X protein inhibitor motif-containing (TMBIM) 6, a Ca2+ channel-like protein, is highly up-regulated in several cancer types. Here, we show that TMBIM6 is closely associated with survival in patients with… read more here.
Keywords: tmbim6; akt activation; cancer; progression ... See more keywords
Expression of TMBIM6 in Cancers: The Involvement of Sp1 and PKC
Sign Up to like & getrecommendations! Published in 2019 at "Cancers"
DOI: 10.3390/cancers11070974
Abstract: Transmembrane Bax Inhibitor Motif-containing 6 (TMBIM6) is upregulated in several cancer types and involved in the metastasis. Specific downregulation of TMBIM6 results in cancer cell death. However, the TMBIM6 gene transcriptional regulation in normal and… read more here.
Keywords: involvement sp1; tmbim6; expression; cancer ... See more keywords