TMC4 localizes to multiple taste cell types in the mouse taste papillae.
Sign Up to like & getrecommendations! Published in 2025 at "FEBS open bio"
DOI: 10.1002/2211-5463.70159
Abstract: Salty taste is mediated through two distinct transduction pathways: the amiloride-sensitive and amiloride-insensitive (AI). Transmembrane channel-like 4 (TMC4), a voltage-dependent chloride channel, has recently been identified as playing a critical role in AI-mediated salt taste… read more here.
Keywords: tmc4; taste cell; taste papillae; cell ... See more keywords
The complexities of salt taste reception: insights into the role of TMC4 in chloride taste detection
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2024.1468438
Abstract: Although salt is an essential substance vital to life, excessive salt intake could cause various health issues. Therefore, new technologies and strategies should be developed to reduce salt intake without compromising taste. However, the underlying… read more here.
Keywords: reception; tmc4; taste; salt taste ... See more keywords