An Ultrasmall SnFe2O4 Nanozyme with Endogenous Oxygen Generation and Glutathione Depletion for Synergistic Cancer Therapy
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202006216
Abstract: The tumor microenvironment (TME) with the characteristics of severe hypoxia, overexpressed glutathione (GSH), and high levels of hydrogen peroxide (H2O2) dramatically limits the antitumor efficiency by monotherapy. Herein, a novel TME‐modulated nanozyme employing tin ferrite… read more here.
Keywords: ultrasmall snfe2o4; therapy; oxygen; glutathione ... See more keywords
Functional CT Contrast Nanoagents for the Tumor Microenvironment.
Sign Up to like & getrecommendations! Published in 2020 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202000912
Abstract: Understanding the detailed tumor microenvironment (TME) is essential to achieve effective treatment of tumor, because TME has an extremely profound influence on the occurrence, development, invasion, and metastasis of tumor. It is of great significance… read more here.
Keywords: tme; tumor microenvironment; functional contrast; contrast nanoagents ... See more keywords
The combined signatures of hypoxia and cellular landscape provides a prognostic and therapeutic biomarker in hepatitis B virus‐related hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Cancer"
DOI: 10.1002/ijc.34045
Abstract: Prognosis and treatment options of hepatitis B virus‐related hepatocellular carcinoma (HBV‐HCC) are generally based on tumor burden and liver function. Yet, tumor growth and therapeutic resistance of HBV‐HCC are strongly influenced by intratumoral hypoxia and… read more here.
Keywords: virus related; related hepatocellular; tme; hepatitis virus ... See more keywords
Computational construction of TME‐related lncRNAs signature for predicting prognosis and immunotherapy response in clear cell renal cell carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24582
Abstract: The tumor microenvironment (TME) is closely related to clear cell renal cell carcinoma (ccRCC) prognosis, and immunotherapy response. In current study, comprehensive bio‐informative analysis was adopted to construct a TME‐related lncRNA signature for immune checkpoint… read more here.
Keywords: cell renal; cell; cell carcinoma; renal cell ... See more keywords
Effects of Exercise on the Tumour Microenvironment.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-35727-6_3
Abstract: Epidemiological evidence suggests that exercise improves survival in cancer patients. However, much is still unknown regarding the mechanisms of this positive survival effect and there are indications that exercise may not be universally beneficial for… read more here.
Keywords: tumour microenvironment; exercise tumour; tme; effects exercise ... See more keywords
IL-23 and the Tumor Microenvironment.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-55617-4_6
Abstract: The tumor microenvironment (TME), which assists in the development, progression, and metastasis of malignant cells, is instrumental in virtually every step of tumor development. While a healthy TME can protect against malignancy, in an unhealthy… read more here.
Keywords: tme; tumor microenvironment; biology; tumor ... See more keywords
Inflammatory Components of the Thyroid Cancer Microenvironment: An Avenue for Identification of Novel Biomarkers.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-83282-7_1
Abstract: The incidence of thyroid cancer in the United States is on the rise with an appreciably high disease recurrence rate of 20-30%. Anaplastic thyroid cancer (ATC), although rare in occurrence, is an aggressive form of… read more here.
Keywords: cancer; tumor; microenvironment; thyroid cancer ... See more keywords
Non-inferiority multicenter prospective randomized controlled study of rectal cancer T2–T3s (superficial) N0, M0 undergoing neoadjuvant treatment and local excision (TEM) vs total mesorectal excision (TME)
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DOI: 10.1007/s00384-017-2942-1
Abstract: PurposeThe standard treatment of rectal adenocarcinoma is total mesorectal excision (TME), in many cases requires a temporary or permanent stoma. TME is associated with high morbidity and genitourinary alterations. Transanal endoscopic microsurgery (TEM) allows access… read more here.
Keywords: non inferiority; treatment; study; excision ... See more keywords
Toxic Metabolic Encephalopathy in Hospitalized Patients with COVID-19
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DOI: 10.1007/s12028-021-01220-5
Abstract: Toxic metabolic encephalopathy (TME) has been reported in 7–31% of hospitalized patients with coronavirus disease 2019 (COVID-19); however, some reports include sedation-related delirium and few data exist on the etiology of TME. We aimed to… read more here.
Keywords: toxic metabolic; etiology; tme; patients covid ... See more keywords
Extended Total Mesorectal Excision (e-TME) for Locally Advanced Rectal Cancer
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Gastrointestinal Cancer"
DOI: 10.1007/s12029-020-00562-1
Abstract: Locally advanced rectal cancer (LARC) can involve surrounding pelvic organs requiring multivisceral resection. Extended total mesorectal excision (e-TME) or multivisceral resection is a complex procedure associated with high morbidity, mortality, and R1 resection rates. However,… read more here.
Keywords: rectal cancer; advanced rectal; tme; cancer ... See more keywords
The tumor microenvironment as driver of stemness and therapeutic resistance in breast cancer: New challenges and therapeutic opportunities.
Sign Up to like & getrecommendations! Published in 2021 at "Cellular oncology"
DOI: 10.1007/s13402-021-00634-9
Abstract: BACKGROUND Breast cancer (BC), the second most common cause of cancer-related deaths, remains a significant threat to the health and wellness of women worldwide. The tumor microenvironment (TME), comprising cellular components, such as cancer-associated fibroblasts… read more here.
Keywords: therapeutic resistance; breast cancer; tme; cancer ... See more keywords