Unconventional secretion: cargo channeling by TMED10
Sign Up to like & getrecommendations! Published in 2020 at "Cell Research"
DOI: 10.1038/s41422-020-0382-x
Abstract: Cytosolic proteins lacking a signal peptide are often loaded into vesicles and secreted via unconventional protein secretion pathways. A recent paper in Cell identifies the transmembrane protein TMED10 as a protein channel for the vesicular… read more here.
Keywords: unconventional secretion; protein; secretion; mil ... See more keywords
TMED10 inhibits mitochondrial damage and protects neurons in ischemic stroke via the JNK signaling pathway.
Sign Up to like & getrecommendations! Published in 2022 at "Experimental animals"
DOI: 10.1538/expanim.22-0060
Abstract: Stroke, a type of acute cerebrovascular disease, is a global disease with high mortality. Neuronal ischemia and hypoxia are closely related to occurrence and development of cognitive impairment. Transmembrane p24 trafficking protein 10 (TMED10) as… read more here.
Keywords: mitochondrial damage; tmed10; tmed10 inhibits; inhibits mitochondrial ... See more keywords