In vivo CRISPR screening reveals nutrient signaling processes underpinning CD8+ T cell fate decisions
Sign Up to like & getrecommendations! Published in 2021 at "Cell"
DOI: 10.1016/j.cell.2021.02.021
Abstract: How early events in effector T cell (TEFF) subsets tune memory T cell (TMEM) responses remains incompletely understood. Here, we systematically investigated metabolic factors in fate determination of TEFF and TMEM cells using in vivo pooled CRISPR screening,… read more here.
Keywords: tmem; crispr screening; cell fate; nutrient signaling ... See more keywords