Transmembrane protein 100 is expressed in neurons and glia of dorsal root ganglia and is reduced after painful nerve injury
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DOI: 10.1097/pr9.0000000000000703
Abstract: Introduction: Tmem100 modulates interactions between TRPA1 and TRPV1. The cell specificity of Tmem100 expression in dorsal root ganglia (DRGs) is not well defined, nor is the effect of peripheral nerve injury on Tmem100 expression. Objective:… read more here.
Keywords: expression; pain; tmem100; nerve injury ... See more keywords
The Role of IL-6 and TMEM100 in Lumbar Discogenic Pain and the Mechanism of the Glycine-Serine-Threonine Metabolic Axis: A Metabolomic and Molecular Biology Study
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DOI: 10.2147/jpr.s400871
Abstract: Background It is well established that discogenic low back pain (DLBP) is often caused by the inflammatory response during intervertebral disc degeneration (IDD). However, it remains unclear how inflammatory mediators such as Interleukin-6 (IL-6) are… read more here.
Keywords: biology; tmem100; pain; metabolic pathways ... See more keywords
TMEM100, a regulator of TRPV1-TRPA1 interaction, contributes to temporomandibular disorder pain
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DOI: 10.3389/fnmol.2023.1160206
Abstract: There is an unmet need to identify new therapeutic targets for temporomandibular disorder (TMD) pain because current treatments are limited and unsatisfactory. TMEM100, a two-transmembrane protein, was recently identified as a regulator to weaken the… read more here.
Keywords: trpa1; tmd pain; tmem100; pain ... See more keywords
The Role of a Lung Vascular Endothelium Enriched Gene TMEM100
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DOI: 10.3390/biomedicines11030937
Abstract: Transmembrane protein 100 (TMEM100) is a crucial factor in the development and maintenance of the vascular system. The protein is involved in several processes such as angiogenesis, vascular morphogenesis, and integrity. Furthermore, TMEM100 is a… read more here.
Keywords: role lung; role; lung; enriched gene ... See more keywords