TMEM147: A Promising Cancer Biomarker Associated with Immune Cell Infiltration and Prognosis in LIHC—Insights from a Comprehensive Pan-Cancer Genomic Analysis
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DOI: 10.1021/acsomega.4c01215
Abstract: Previous studies have demonstrated the regulatory roles of Transmembrane protein 147 (TMEM147) in various diseases, including cancer. However, systematic pan-cancer analyses investigating the role of TMEM147 in diagnosis, prognosis, and immunological prediction are lacking. An… read more here.
Keywords: cancer; analysis; prognosis; cell ... See more keywords
TMEM147 interacts with Lamin B Receptor, regulates its localization and levels, and affects cholesterol homeostasis.
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DOI: 10.1242/jcs.245357
Abstract: The structurally and functionally complex Endoplasmic Reticulum (ER) hosts critical processes including lipid synthesis. Here, we focus on the functional characterization of transmembrane protein TMEM147 and report that it localizes at the ER and nuclear… read more here.
Keywords: lamin receptor; lbr; cholesterol homeostasis; tmem147 ... See more keywords