Spinal Motoneuron TMEM16F Acts at C-boutons to Modulate Motor Resistance and Contributes to ALS Pathogenesis.
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.02.001
Abstract: Neuronal Ca2+ entry elicited by electrical activity contributes to information coding via activation of K+ and Cl- channels. While Ca2+-dependent K+ channels have been extensively studied, the molecular identity and role of Ca2+-activated Cl- channels… read more here.
Keywords: motor resistance; motoneuron tmem16f; spinal motoneuron; motor ... See more keywords
Single-molecule analysis of phospholipid scrambling by TMEM16F
Sign Up to like & getrecommendations! Published in 2018 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1717956115
Abstract: Significance Membrane proteins that translocate various compounds across biological membranes play important roles in maintaining intracellular homeostasis in cells. Scramblases are membrane proteins that translocate phospholipids between the inner and outer leaflets of the plasma… read more here.
Keywords: molecule; single molecule; scramblase; phospholipid scrambling ... See more keywords
Regulation and Function of TMEM16F in Renal Podocytes
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DOI: 10.3390/ijms19061798
Abstract: The Ca2+-activated phospholipid scramblase and ion channel TMEM16F is expressed in podocytes of renal glomeruli. Podocytes are specialized cells that form interdigitating foot processes as an essential component of the glomerular filter. These cells, which… read more here.
Keywords: ca2 activated; ca2; tmem16f; regulation function ... See more keywords