Gut dysbiosis and neuroimmune responses to brain infection with Theiler’s murine encephalomyelitis virus
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep44377
Abstract: Recent studies have begun to point out the contribution of microbiota to multiple sclerosis (MS) pathogenesis. Theiler’s murine encephalomyelitis virus induced demyelinating disease (TMEV-IDD) is a model of progressive MS. Here, we first analyze the… read more here.
Keywords: encephalomyelitis virus; murine encephalomyelitis; tmev; theiler murine ... See more keywords
Theiler's Virus-Mediated Immunopathology in the CNS and Heart: Roles of Organ-Specific Cytokine and Lymphatic Responses
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.02870
Abstract: Theiler's murine encephalomyelitis virus (TMEV) induces different diseases in the central nervous system (CNS) and heart, depending on the mouse strains and time course, with cytokines playing key roles for viral clearance and immune-mediated pathology… read more here.
Keywords: immunopathology; tmev; pathology; cns heart ... See more keywords
Viral Clearance and Neuroinflammation in Acute TMEV Infection Vary by Host Genetic Background
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231810482
Abstract: A wide range of viruses cause neurological manifestations in their hosts. Infection by neurotropic viruses as well as the resulting immune response can irreversibly disrupt the complex structural and functional architecture of the brain, depending… read more here.
Keywords: acute; background; tmev; genetic background ... See more keywords