Articles with "tmpo as1" as a keyword



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LncRNA TMPO‐AS1 serves as a ceRNA to promote osteosarcoma tumorigenesis by regulating miR‐199a‐5p/WNT7B axis

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Published in 2019 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.29451

Abstract: Osteosarcoma (OS) is a common kind of aggressive tumor in bone which was mostly identified in children and adolescents with extremely high risk of death. Accumulating research works have displayed that long noncoding RNAs (lncRNAs)… read more here.

Keywords: mir 199a; wnt7b; tmpo as1; as1 serves ... See more keywords
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lncRNA TMPO antisense RNA 1 promotes the malignancy of cholangiocarcinoma cells by regulating let-7g-5p/ high-mobility group A1 axis

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Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2022.2025700

Abstract: ABSTRACT Cholangiocarcinoma (CHOL) is often diagnosed at an advanced stage; therefore, exploring its key regulatory factors is important for earlier diagnosis and treatment. This study aimed to identify the mechanisms of long non-coding RNA (lncRNA)… read more here.

Keywords: chol; rna; tmpo as1; tmpo ... See more keywords
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Proliferation‐associated long noncoding RNA, TMPO‐AS1, is a potential therapeutic target for triple‐negative breast cancer

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Published in 2020 at "Cancer Science"

DOI: 10.1111/cas.14498

Abstract: Triple‐negative breast cancer (TNBC) is an aggressive subtype of breast cancer compared with luminal or epidermal growth factor receptor 2 subtypes, thus effective therapeutic options for TNBC are yet to be developed. Nowadays, oncogenic long… read more here.

Keywords: tmpo as1; proliferation; breast cancer; tnbc ... See more keywords
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Long noncoding RNA TMPO‐AS1/miR‐126‐5p/BRCC3 axis accelerates gastric cancer progression and angiogenesis via activating PI3K/Akt/mTOR pathway

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Published in 2020 at "Journal of Gastroenterology and Hepatology"

DOI: 10.1111/jgh.15362

Abstract: Gastric cancer (GC) is an aggressive tumor featured by uncontrolled cell proliferation and metastasis. In recent years, long noncoding RNAs (lncRNAs) act as crucial regulators and biological markers in multiple cancers. LncRNA TMPO‐AS1 has been… read more here.

Keywords: gastric cancer; long noncoding; tmpo as1;
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LncRNA TMPO-AS1 facilitates the proliferation and metastasis of NSCLC cells by up-regulating ERBB2 via sponging miR-204-3p

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Published in 2020 at "International Journal of Immunopathology and Pharmacology"

DOI: 10.1177/2058738420958947

Abstract: Introduction: This study aims at probing into the expression and biological function of long non-coding RNA (lncRNA) TMPO-AS1 in non-small cell lung cancer (NSCLC), and exploring its regulatory role for miR-204-3p and erb-b2 receptor tyrosine… read more here.

Keywords: mir 204; expression; tmpo as1; nsclc cells ... See more keywords
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Long Non-Coding RNA TMPO-AS1 Promotes GLUT1-Mediated Glycolysis and Paclitaxel Resistance in Endometrial Cancer Cells by Interacting With miR-140 and miR-143

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Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.912935

Abstract: Increased glycolysis in tumor cells is frequently associated with drug resistance. Overexpression of glucose transporter-1 (GLUT1) promotes the Warburg effect and mediates chemoresistance in various cancers. Aberrant GLUT1 expression is considered as an essential early… read more here.

Keywords: mir; glycolysis; resistance; tmpo as1 ... See more keywords
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Inhibition of lncRNA TMPO-AS1 suppresses proliferation, migration and invasion of colorectal cancer cells by targeting miR-143-3p

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Published in 2020 at "Molecular Medicine Reports"

DOI: 10.3892/mmr.2020.11427

Abstract: Long non-coding RNAs (lncRNAs) are widely studied in cancer pathogenesis. Accumulating evidence has demonstrated that lncRNAs are involved in the cellular progression of colorectal cancer (CRC). However, the regulatory mechanism of lncRNA TMPO-antisense (AS)1 in… read more here.

Keywords: proliferation migration; mir 143; tmpo as1; crc ... See more keywords