Genetic association of TMPRSS2 rs2070788 polymorphism with COVID-19 case fatality rate among Indian populations
Sign Up to like & getrecommendations! Published in 2022 at "Infection, Genetics and Evolution"
DOI: 10.1016/j.meegid.2022.105206
Abstract: SARS-CoV2, the causative agent for COVID-19, an ongoing pandemic, engages the ACE2 receptor to enter the host cell through S protein priming by a serine protease, TMPRSS2. Variation in the TMPRSS2 gene may account for… read more here.
Keywords: tmprss2; tmprss2 gene; gene; rs2070788 ... See more keywords
A Polymorphism in the TMPRSS2 Gene Increases the Risk of Death in Older Patients Hospitalized with COVID-19
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14112557
Abstract: Background: Transmembrane serine protease type 2 (TMPRSS2) and angiotensin-converting enzyme 2 (ACE2) are the main molecules involved in the entry of SARS-CoV-2 into host cells. Changes in TMPRSS2 expression levels caused by single nucleotide polymorphisms… read more here.
Keywords: polymorphism tmprss2; older patients; death; risk death ... See more keywords