Articles with "tmprss4" as a keyword



Molecular mechanisms of lncRNA SMARCC2/miR-551b-3p/TMPRSS4 axis in gastric cancer.

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Published in 2018 at "Cancer letters"

DOI: 10.1016/j.canlet.2018.01.032

Abstract: Decreased expression of miR-551b-3p has been identified in gastric cancer tissues but its biological role and underlying mechanism in this malignancy is poorly understood. In this study, we show that the expression of miR-551b-3p negatively… read more here.

Keywords: gastric cancer; tmprss4; lncrna smarcc2; cancer ... See more keywords

TMPRSS4 as a prognostic biomarker after gastric cancer surgery in a multicenter retrospective study

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Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-025-93422-6

Abstract: Transmembrane protease serine 4 (TMPRSS4) is a member of the type II transmembrane serine protease family known to be upregulated in many malignancies. We previously showed that TMPRSS4 may be a prognostic biomarker and therapeutic… read more here.

Keywords: group; gastric cancer; prognostic biomarker; tmprss4 ... See more keywords
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COVID-19 and SARS-CoV-2 host cell entry mediators: Expression profiling of TMRSS4 in health and disease

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Published in 2021 at "International Journal of Molecular Medicine"

DOI: 10.3892/ijmm.2021.4897

Abstract: Severe acute respiratory syndrome (SARS) coronavirus-2 (SARS-CoV-2), the causative viral agent for the ongoing COVID-19 pandemic, enters its host cells primarily via the binding of the SARS-CoV-2 spike (S) proteins to the angiotensin-converting enzyme 2… read more here.

Keywords: entry mediators; tmprss4; cell entry; sars cov ... See more keywords

The upregulation of TMPRSS4, partly ascribed to the downregulation of miR-125a-5p, promotes the growth of human lung adenocarcinoma via the NF-κB signaling pathway

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Published in 2018 at "International Journal of Oncology"

DOI: 10.3892/ijo.2018.4396

Abstract: In this study, with the aid of microarray technology, transmembrane protease serine 4 (TMPRSS4), a novel member of the serine protease family, was found to be upregulated in the majority of lung adenocarcinoma (LUAD) tissues… read more here.

Keywords: lung adenocarcinoma; tmprss4; signaling pathway; partly ascribed ... See more keywords