P174 Transmembrane TNF transgenic mice exhibit enlarged lymph nodes and elevated numbers of high endothelial cells associated with increased lymphocyte recruitment
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-ewrr2019.156
Abstract: Career situation of first and presenting author Post-doctoral fellow. Introduction NF-κB signaling plays a crucial role in chronic inflammatory diseases and can be activated via two pathways. Noncanonical NF-κB signaling can be induced by different… read more here.
Keywords: mln; pln 106; tmtnf mice; 106 106 ... See more keywords
FRI0367 INFLAMMATORY PROCESSES IN EXPERIMENTAL SPONDYLOARTHRITIS ARE ACCOMPANIED BY FORMATION OF ECTOPIC LYMPHOID STRUCTURES IN THE BONE MARROW AND ALTERATIONS IN THE B CELL LINEAGE
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2019-eular.6864
Abstract: Background Tumour necrosis factor (TNF) is important in immune-mediated inflammatory diseases such as spondyloarthritis (SpA). SpA patients have extensive angiogenesis in inflammatory and bone forming regions. Transmembrane (tm)TNF-transgenic (tg) mice (1) that overexpress tmTNF develop… read more here.
Keywords: tmtnf mice; bone; none declared; mice ... See more keywords