Tembusu Virus Nonstructural Protein 2B Antagonizes Type I Interferon Production by Targeting MAVS for Degradation
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Virology"
DOI: 10.1128/jvi.00816-22
Abstract: Tembusu virus (TMUV), an emerging pathogenic flavivirus, has spread to most duck farming areas in Asia since 2010, causing significant economic losses to the duck industry. Recently, TMUV has expanded its host range and may… read more here.
Keywords: host; degradation; tmuv; tembusu virus ... See more keywords
The difference in CD4+ T cell immunity between high- and low-virulence Tembusu viruses is mainly related to residues 151 and 304 in the envelope protein
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.890263
Abstract: Tembusu virus (TMUV) can result in a severe disease affecting domestic ducks. The role of T cells in protection from TMUV infection and the molecular basis of T cell-mediated protection against TMUV remain largely uncharacterized.… read more here.
Keywords: cell; cd4; immunity; low virulence ... See more keywords
Chicken-origin Cluster 3.2 Tembusu virus exhibits higher infectivity than duck-origin Cluster 2 Tembusu virus in chicks
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2023.1152802
Abstract: In 2020, a chicken-origin Cluster 3 Tembusu virus (TMUV) caused outbreaks of a disease characterized by egg-drop syndrome in laying hens in China. In the present study, a TMUV strain, TMUV-GX, was isolated from tissue… read more here.
Keywords: origin cluster; chicken origin; cluster; cluster tembusu ... See more keywords
A Single Mutation at Position 120 in the Envelope Protein Attenuates Tembusu Virus in Ducks
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DOI: 10.3390/v14030447
Abstract: A live attenuated duck Tembusu virus (TMUV) vaccine FX2010-180P (180P) was successfully utilized to prevent TMUV infections in ducks in China. Compared with wild-type TMUV, 180P was highly attenuated and lost transmissibility in ducks. However,… read more here.
Keywords: transmissibility; attenuation; envelope protein; tembusu virus ... See more keywords
The Evolution, Genomic Epidemiology, and Transmission Dynamics of Tembusu Virus
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DOI: 10.3390/v14061236
Abstract: Tembusu virus (TMUV) can induce severe egg drop syndrome in ducks, causing significant economic losses. In this study, the possible origin, genomic epidemiology, and transmission dynamics of TMUV were determined. The time to the most… read more here.
Keywords: tembusu virus; epidemiology transmission; genomic epidemiology; tmuv ... See more keywords