Wnt Signaling Regulates MFSD2A-dependent Drug Delivery through Endothelial Transcytosis in Glioma.
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DOI: 10.1093/neuonc/noac288
Abstract: BACKGROUND Systemic delivery of anti-tumor therapeutic agents to brain tumors is thwarted by the blood-brain barrier (BBB), an organotypic specialization of brain endothelial cells (ECs). A failure of pharmacological compounds to cross BBB is one… read more here.
Keywords: signaling regulates; transcytosis; tmz delivery; glioma ... See more keywords