The role of ENSO flavours and TNA on recent droughts over Amazon forests and the Northeast Brazil region
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Climatology"
DOI: 10.1002/joc.6453
Abstract: Amazon tropical forests and the semiarid Northeast Brazil (NEB) region have registered very severe droughts during the last two decades, with a frequency that may have exceeded natural climate variability. Severe droughts impact the physiological… read more here.
Keywords: neb region; tna; amazon forests; northeast brazil ... See more keywords
Tanshinone IIA harmonizes the crosstalk of autophagy and polarization in macrophages via miR‐375/KLF4 pathway to attenuate atherosclerosis
Sign Up to like & getrecommendations! Published in 2019 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2019.02.054
Abstract: Abstract Macrophages play a pivotal role in destabilizing atherosclerotic plaque. The diverse phenotypes and complex autophagy in macrophage are observed in atherosclerotic lesions. Tanshinone IIA (TNA) is known as the major component extracted from the… read more here.
Keywords: autophagy polarization; tna; tanshinone iia; mir 375 ... See more keywords
A Nucleic Acid Sequence That is Catalytically Active in Both RNA and TNA Backbones.
Sign Up to like & getrecommendations! Published in 2022 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.2c00479
Abstract: Threose nucleic acid (TNA) is considered a potential RNA progenitor due to its chemical simplicity, base pairing property, and capability of folding into a functional tertiary structure. However, it is unknown whether the functional property… read more here.
Keywords: tna rna; tna; sequence catalytically; rna ... See more keywords
Generating Biologically Stable TNA Aptamers that Function with High Affinity and Thermal Stability.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.0c00641
Abstract: Aptamers generated from natural and modified nucleo-tides are often prone to nuclease digestion, which limits their utility in many biomedical applications, including therapeutics. Here we describe the in vitro selection of an unnatural nucleic acid… read more here.
Keywords: affinity thermal; tna aptamers; tna; thermal stability ... See more keywords
Tanshinone IIA Promotes M2 Microglia by ERβ/IL-10 Pathway and Attenuates Neuronal Loss in Mouse TBI Model
Sign Up to like & getrecommendations! Published in 2020 at "Neuropsychiatric Disease and Treatment"
DOI: 10.2147/ndt.s265478
Abstract: Purpose Traumatic brain injury (TBI) is a major cause of morbidity and mortality worldwide. Increasing evidence indicates that activated microglia play an important role in the inflammatory response in TBI. Inhibiting M1 and stimulating M2… read more here.
Keywords: tna; tbi model; mouse tbi; tbi ... See more keywords
The Impact and Clinical Prediction of Hyperglycemia During Parenteral Nutrition for Nondiabetic Patients After Gastrectomy for Gastric Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2022.807841
Abstract: Background and Purpose Hyperglycemia (HG) is associated with increased postoperative complications. This study aims to evaluate the effect of HG during supplemental parenteral nutrition (SPN) on short-term prognosis in non-diabetic patients undergoing gastrectomy for cancer… read more here.
Keywords: tna; hyperglycemia; parenteral nutrition; factors severe ... See more keywords