TNFα blockade overcomes resistance to anti-PD-1 in experimental melanoma
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/s41467-017-02358-7
Abstract: Antibodies against programmed cell death-1 (PD-1) have considerably changed the treatment for melanoma. However, many patients do not display therapeutic response or eventually relapse. Moreover, patients treated with anti-PD-1 develop immune-related adverse events that can… read more here.
Keywords: melanoma; tnf blockade; tnf; blockade ... See more keywords
TNF-α blockade may lead to improvement of vascular function in psoriasis patients.
Sign Up to like & getrecommendations! Published in 2021 at "Experimental dermatology"
DOI: 10.1111/exd.14452
Abstract: Psoriasis is one of the most common chronic inflammatory skin diseases and at the same time a risk factor for cardiovascular disease. Interleukin-17A (IL-17A)-mediated inflammation in psoriasis may lead to vascular dysfunction. This study aimed… read more here.
Keywords: tnf blockade; treatment; vascular function; psoriasis patients ... See more keywords
04.15 Resolution of systemic inflammatory processes and regeneration of inflammation-driven bone damage upon tnf blockade as monitored by in vivo multimodal pet-ct imaging in tnf driven experimental arthritis
Sign Up to like & getrecommendations! Published in 2017 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2016-211051.15
Abstract: Objective To use in vivo multimodal [18F]FDG (fluoro-D-glucose, tracer for inflammation) and [18F]sodium fluoride (bone tracer) positron emission tomography/computed tomography (PET-CT) imaging for the monitoring of systemic inflammatory and bone remodelling processes as well as… read more here.
Keywords: tnf blockade; pet; tnf; bone ... See more keywords
TNFα Blockade in Checkpoint Inhibition: The Good, the Bad, or the Ugly?
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Cancer Research"
DOI: 10.1158/1078-0432.ccr-20-0387
Abstract: The impact on survival of steroids and TNFα blockade to treat immune-related toxicity from checkpoint blockade with ipilimumab, nivolumab/pembrolizumab, or combined ipilimumab and nivolumab was assessed using data from a large national database. Using steroids… read more here.
Keywords: tnf blockade; blockade checkpoint; good bad; checkpoint inhibition ... See more keywords
TNF-α blockade suppresses pericystic inflammation following anthelmintic treatment in porcine neurocysticercosis
Sign Up to like & getrecommendations! Published in 2017 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0006059
Abstract: Background Neurocysticercosis (NCC) is an infection of the brain with the larval cyst of the tapeworm, Taenia solium. Cysticidal treatment induces parasite killing resulting in a post inflammatory response and seizures, which generally requires corticosteroid… read more here.
Keywords: tnf blockade; dex; neurocysticercosis; treatment ... See more keywords
Tumor necrosis factor-α blockade treatment decreased CD154 (CD40-ligand) expression in rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0183726
Abstract: Contexts CD154 (commonly referred to as CD40-ligand) is a critical T cell factor that participates in the pathogenesis of autoimmune and is over-expressed in rheumatoid arthritis (RA). TNF-α blockade treatment had dramatic efficacy in RA.… read more here.
Keywords: tnf blockade; treatment; cd154; expression ... See more keywords
TNFα Blockade Inhibits Both Initial and Continued Control of Pulmonary Coccidioides
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2021.796114
Abstract: Tumor necrosis factor alpha (TNFα) is a pluripotent cytokine that is important in many infections, though its role in Coccidioides infection remains poorly understood. The need to understand TNFα in Coccidioides infection has increased recently… read more here.
Keywords: infection; control; tnf blockade; b6d2f1 mice ... See more keywords